ReFissa is available by prescription only and is clinically proven to be effective to diminish fine facial wrinkles, fade irregular pigmentation due to sun damage, and/or smooth your skin so it’s softer to the touch (tactile roughness). Refissa is approved by the FDA. Refissa is the only 0.05%-strong prescription tretinoin cream that’s fragrance-free with a moisturizing, emollient base.

Visit or call 1800-FDA-1088. Please see full Prescribing Information and Patient Package Insert. ReFissa is a registered trademark of ZO® Skin Health, Inc. © 2017 ZO® Skin Health, Inc. All rights reserved.

Click here to visit the ReFissa website.
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